Life Extension, 5-Lox Inhibitor with ApresFlex, 100 mg, 60 Vegetarian Capsules


Life Extension

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  • Next Generation Boswellia Extract
  • Dietary Supplement
5-LOX Inhibitor with AprèsFlex® is made with a standardized Boswellia serrata extract that promotes a healthy inflammatory response and absorbs 52% better than standard boswellia extracts.

Compounds in Boswellia extract have been shown to bind directly to 5-LOX, an enzyme that transforms fatty acids into inflammatory factors like leukotriene B4.. A compound in boswellia called AKBA is the key to this beneficial action. Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia.

AprèsFlex® absorbs 52% more than standard boswellia extract and is standardized for the active AKBA compound.

5-LOX Inhibitor with AprèsFlex® Benefits
  • Made with standardized Boswellia serrata extract 
  • Promotes a healthy inflammatory response by inhibiting 5-LOX enzyme 
  • Supports joint health, arterial health & healthy cell division
5-lipoxygenase (5-LOX) is an enzyme that transforms fatty acids into leukotrienes. Since 5-LOX levels increase over time, excess 5-LOX has been linked to some of the common effects of normal aging.

Boswellia extract inhibits 5-LOX

The Indian plant Boswellia serrata contains compounds shown to inhibit 5-LOX to support joint and arterial health. Boswellia inhibits 5-LOX at the cellular level. Scientific data reveals that a compound in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid) is the key to this beneficial action. But boswellia compounds are poorly absorbed into the blood. For this reason, we’ve used AprèsFlex®, a standardized form of boswellia extract. AprèsFlex® absorbs into the blood 52% more than previously available boswellia extracts.

Dietary factors increase 5-LOX prevalence

The typical American diet adds to 5-LOX levels. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger production of arachidonic acid. The body produces 5-LOX enzyme in response to arachidonic acid.

Benefits of modulating 5-LOX

5-LOX creates compounds like leukotriene B4 out of arachidonic acid. Inhibiting leukotriene B4 helps support joint, arterial and tissue health. Inhibiting 5-LOX also helped support healthy cell division in preclinical models. Each 100 mg vegetarian capsule of 5-LOX Inhibitor with AprèsFlex® is standardized to provide 20% of active AKBA from boswellia. Most people need only one capsule a day.

Suggested Use

Read the entire label and follow the directions carefully prior to use.

To inhibit the 5-lipoxygenase enzyme, take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner.

Other Ingredients

Microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.


  • Keep out of reach of children.
  • Do not exceed recommended dose.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Store tightly closed in a cool, dry place.


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Supplement Facts
Serving Size: 1 Vegetarian Capsule
  Amount Per Capsule % Daily Value
ApresFlex (Boswellia serrata) extract (gum resin) [std. to 20% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) (20 mg)] 100 mg **
**Daily Value not established